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S.E.M.I. – Side Effects May Include...
A vibrant game scene from S.E.M.I. – Side Effects May Include... with floating structures, a tower, and a quirky character.
A group of cartoony figures in a colorful game environment with a duck and stairs. S.E.M.I. - Side Effects May Include...
S.E.M.I. - Side Effects May Include... game. Characters in a hospital setting with beds and a checkered floor. Two are in the center, arms raised.
A chaotic scene from S.E.M.I. game. A character in a lab, surrounded by fire, with various obstacles and elements.

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    Patch Notes

    • #1 - 11/24/25 (Early Access, Patch #1: Hot on the Trail)
    • 10/13/25 (Meet the Lobby System! Now Escape is a Team Effort!)
    • #1 - 10/2/25 (Demo Update #1: Mine Cart Room, Enemy Behavior, and Other Improvements)

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    • Technical information

    • Official website
    • Categories : Action
    • Editor : Two Horn Unicorn
    • Developer : Two Horn Unicorn
    • Mode(s) : Solo, Multiplayer, Co-op
    • Release date : November 20, 2025
    • Latest patch: #1 - 11/24/25
    • System Requirements
      • Minimum
      • OS: Windows 10 (64 bit)
      • CPU : Core i5-12400T
      • RAM : 8 GB
      • GPU : GeForce GTX 960 / Radeon R9 290
      • Storage : 3 GB
      • Recommended
      • OS: Windows 11 (64 bit)
      • CPU : Core i7-610
      • RAM : 8 GB
      • GPU : GeForce GTX 1660 / Radeon RX6600
      • Storage : 3 GB
    • Age Rating
    • PEGI 12 ESRB E10
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